
Allergy Medicines
Allergy medicines are commonly used in primary care to manage symptoms such as sneezing, itching, watery eyes, nasal congestion, skin rashes, and hives. They can help with conditions such as hay fever, allergic rhinitis, urticaria (hives), and mild allergic reactions.
Treatment depends on symptom pattern, severity, triggers, and whether the reaction is mild and localised or more widespread. Some allergy medicines are taken only when needed, while others work best when used regularly during allergy seasons.
This page explains the main types of allergy medicines used in general practice, how they work, and what safety considerations apply.
These articles are intended as educational sources, not diagnostic nor taking place of a proper medical assessment. If you need help, please book an appointment with one of our GP’s.
Why allergy treatment matters
Allergy symptoms can significantly affect sleep, concentration, work performance, and quality of life. In some people, allergic inflammation can also worsen asthma or other respiratory symptoms.
Treatment is usually aimed at:
- controlling symptoms
- reducing inflammation
- preventing flare-ups during predictable seasons
- identifying triggers where possible
Main Types of Allergy Medicines
Antihistamine tablets
Antihistamines reduce the effects of histamine, a chemical released during allergic reactions. They are commonly used for hay fever, itching, and hives.
Common examples include cetirizine, loratadine, and fexofenadine.
Some antihistamines can cause drowsiness, especially older types. If you drive or operate machinery, it is important to check whether your medication is sedating.
Antihistamine eye drops
Eye drops can be helpful for itchy, watery, red eyes caused by allergies. They may be used alone or alongside oral antihistamines.
A GP can advise which type is most suitable based on symptom pattern and severity.
Nasal steroid sprays
Nasal steroid sprays reduce inflammation in the nasal passages and are often one of the most effective treatments for persistent allergic rhinitis, especially when congestion is the main symptom.
Common examples include fluticasone and mometasone.
These sprays work best when used consistently during symptomatic periods. They often take several days to reach full effect.
Nasal antihistamine sprays
Antihistamine sprays can help relieve nasal symptoms and may work more quickly for some people. They are sometimes used alongside nasal steroids.
Decongestants
Decongestants can reduce nasal blockage for short periods. They may be found in sprays or tablets.
They are usually not recommended for prolonged use. Overuse of decongestant nasal sprays can cause rebound congestion, where blockage becomes worse when the spray is stopped.
Decongestants may not be suitable for people with certain heart conditions or uncontrolled high blood pressure.
Skin treatments for allergy symptoms
For skin allergy symptoms such as eczema flares or allergic rashes, treatment may include:
- moisturisers and barrier creams
- topical steroids for inflammation
- antihistamines for itch relief
Topical steroid use should be appropriate to the area and severity, and reviewed if symptoms persist.
You can read more in: Steroids explained
Adrenaline auto-injectors and severe allergy
Adrenaline auto-injectors are used for severe allergic reactions (anaphylaxis) and are usually prescribed following specialist assessment or a clear clinical indication.
If someone has a history of anaphylaxis or severe allergic reactions, they should have an individualised action plan.
Red flags: severe allergic reaction (anaphylaxis)
Seek urgent medical help immediately if any of the following occur during an allergic reaction.
What to do: Call 999 immediately if anaphylaxis is suspected. If prescribed an adrenaline auto-injector, use it without delay and seek emergency medical care even if symptoms begin to improve.
Monitoring and Long-Term Review
Allergy medicines do not usually require blood test monitoring. However, review can be helpful if:
- symptoms are persistent despite treatment
- asthma symptoms worsen alongside allergies
- side effects occur
- the diagnosis is uncertain
Where symptoms are severe or recurrent, further assessment may be needed.
You can read more in:
Common Side Effects and Safety
Most allergy medicines are well tolerated. Possible side effects include:
- drowsiness with some antihistamines
- dry mouth
- nosebleeds or irritation with nasal sprays
- rebound congestion with prolonged decongestant spray use
Medication choice is often guided by symptom type, severity, and safety for work, driving, or pregnancy.
Allergy Medicines in Remote GP Care
Allergy symptoms can often be assessed remotely. A GP may ask about triggers, seasonal patterns, associated asthma symptoms, and response to treatments tried.
If symptoms suggest a more serious cause, recurrent infections, or nasal polyps, in-person assessment or referral may be recommended.
Frequently Asked Questions
1. What is the best treatment for hay fever?
Many people benefit from a combination of a non-drowsy antihistamine tablet and a nasal steroid spray. The best choice depends on your main symptoms, severity, and how often symptoms occur.
2. Why do nasal steroid sprays take time to work?
Nasal steroid sprays reduce inflammation rather than providing immediate decongestion. They often take several days of consistent use to reach full effect.
3. Can allergy medicines make me drowsy?
Yes. Some antihistamines can cause drowsiness, particularly older types. If you drive or operate machinery, it is important to choose a non-drowsy option and check the leaflet advice.

When to contact a GP
You should consider contacting a GP if:
- symptoms persist despite appropriate treatment
- you have recurrent wheeze or breathlessness alongside allergies
- you have facial swelling, severe hives, or widespread reactions
- symptoms interfere with sleep or daily life
- you are unsure which medicine is most appropriate
If you develop breathing difficulty, swelling of the lips or tongue, collapse, or severe allergic symptoms, seek urgent or emergency care immediately.

Related articles
Further Reading and Hub Links
Visit our Medication and Prescribing hub or browse more health topics in the AccessGP Knowledge Base.
If you are worried about allergy symptoms, asthma flare-ups, or severe reactions, a GP can help guide you on the safest next step.
Last reviewed by Dr Zamiel Hussain, GMC registered GP
Updated: 11 February 2026
