This section includes GP reviewed summaries of common hormone related topics seen in primary care. The articles describe how hormone changes may present, which blood tests are sometimes considered and how GPs decide on the most appropriate next steps.
The topics include:

  • thyroid hormone balance
  • testosterone and men’s hormone health
  • oestrogen and progesterone
  • perimenopause and menopause
  • polycystic ovary syndrome (PCOS)
  • fertility related markers such as FSH, LH and AMH
  • prolactin
  • cortisol and adrenal hormones

Each article provides clear, non diagnostic information based on current clinical understanding.

Adults may raise possible hormone issues when they notice changes such as:

  • ongoing fatigue, low energy or “brain fog”
  • weight gain or weight loss without clear explanation
  • feeling unusually hot or cold, sweating or palpitations
  • menstrual changes, irregular periods or heavy bleeding
  • reduced libido, erectile difficulties or changes in muscle mass
  • mood change around the menstrual cycle or midlife
  • difficulty conceiving or concerns about fertility
  • hair thinning, acne or excess facial hair

In private GP care, hormone concerns are usually explored through a detailed history, review of lifestyle factors and consideration of targeted blood tests where appropriate.

Below is an overview of the main hormone health areas covered.
Each has a dedicated article for more detail.

Thyroid function tests, usually starting with TSH and often including free T4, help assess whether the thyroid gland is underactive or overactive. Symptoms can include tiredness, weight change, sensitivity to cold or heat, and mood changes. Thyroid blood tests are interpreted alongside symptoms and examination.

Testosterone testing may be considered when men report low energy, reduced libido, erectile difficulties, loss of muscle mass or reduced motivation. Results are always interpreted in the context of sleep, stress, weight, medicines, alcohol and other health conditions. Further assessment may involve repeat testing and discussion about lifestyle as well as wider hormone balance.

Oestrogen and progesterone fluctuate naturally throughout the menstrual cycle and across a woman’s life course. GP assessment of cyclical mood change, heavy or irregular periods and PMS-type symptoms often focuses initially on the pattern of symptoms and contraception history. Blood tests such as FSH, LH and oestradiol may be considered in certain situations.

FSH and LH are pituitary hormones involved in ovulation and sperm production. AMH may be used as an ovarian reserve marker in certain fertility discussions. Prolactin can be checked when periods are absent or there is unexplained breast milk production. These tests are usually arranged in a structured way and often in collaboration with fertility specialists.

Cortisol helps regulate stress responses, energy and blood pressure. Adrenal hormone testing is less common in routine GP practice and is usually guided by specific symptoms and specialist advice. It is not routinely used to investigate general tiredness without other concerning features.

Perimenopause and menopause can cause symptoms such as hot flushes, night sweats, sleep problems, mood change, cycle changes and joint pains. Diagnosis is usually based on age and symptoms rather than blood tests alone. A GP may discuss lifestyle measures, non hormonal options and, where appropriate, hormone replacement therapy, as well as when to consider blood tests.

PCOS is a common condition associated with irregular periods, acne, excess hair growth and weight gain in some women. Assessment may include history, examination, blood tests such as androgens, FSH, LH and sometimes ultrasound. Management often involves lifestyle advice and tailored treatment options.

Hormonal changes during the menstrual cycle can cause symptoms such as mood swings, irritability, bloating, breast tenderness and headaches. In severe cases, symptoms may indicate premenstrual dysphoric disorder (PMDD). Diagnosis is based on symptoms rather than blood tests. A GP may discuss cycle tracking, lifestyle strategies, medical options and when hormone treatments may be appropriate.


If you would like to discuss hormone symptoms, review hormone blood tests or plan a wider health assessment, you can book an online GP appointment with AccessGP.

Last reviewed by Dr Zamiel Hussain, GMC registered GP
Updated: 7 December 2025