
Nail changes and infections
Nail changes are common and can affect fingernails or toenails. Changes in colour, thickness, or shape may be due to infection, skin conditions, injury, or underlying health issues. While many nail problems are harmless, some require assessment and treatment.
This page explains common nail changes, causes, and when to seek GP advice.
These articles are intended as educational sources, not diagnostic nor taking place of a proper medical assessment. If you need help with skin concerns, please book an appointment. We also offer specialist GP dermatology input at the Skin Clinic.
Common nail changes and symptoms
SNail problems may present as:
- Thickened or brittle nails
- Yellow, white, or discoloured nails
- Crumbly or distorted nail edges
- Separation of the nail from the nail bed
- Pitting or ridging of the nail surface
- Pain or redness around the nail
Toenails are more commonly affected by infection than fingernails.
Common causes of nail changes
Fungal nail infection
Fungal infections are a common cause of thickened, discoloured, or crumbly nails. They often develop slowly and may follow athlete’s foot.
Nail psoriasis
Psoriasis can affect the nails, causing pitting, thickening, discoloration, or separation from the nail bed.
Trauma or pressure
Repeated injury or pressure, particularly to toenails, can cause thickening, colour changes, or nail loss.
Other causes
Nail changes may also be linked to:
- Eczema or dermatitis around the nail
- Bacterial infection
- Underlying medical conditions
- Age related nail changes
Correct diagnosis is important, as treatments vary.
How a GP assesses nail problems
A GP will assess nail problems by reviewing symptoms and examining the nails. They may ask about:
- Duration and progression of nail changes
- Involvement of one or multiple nails
- Associated skin conditions
- History of trauma or pressure
- Previous treatments
Photographs are often helpful for remote assessment.
Investigations
Nail sampling may be recommended if a fungal infection is suspected, particularly before starting long term treatment.
Blood tests are not usually required unless another underlying condition is suspected.
Self care and nail care measures
Good nail care can help prevent worsening:
- Keep nails trimmed and clean
- Avoid sharing nail clippers or tools
- Keep feet dry and change socks regularly
- Wear well fitting footwear
- Avoid nail cosmetics during treatment
Nail changes often take months to improve as nails grow slowly.
Medical treatments a GP may recommend
Treatment depends on the underlying cause. A GP may recommend:
- Antifungal treatments for confirmed fungal infection
- Topical treatments for nail psoriasis or dermatitis
- Advice on footwear and nail care
- Referral if diagnosis is uncertain or treatment fails
Treatment response can take several months.

When to seek GP review
You should consider a GP appointment if:
- Nail changes are persistent or worsening
- You notice an unusual appearance or colour to your nails
- Multiple nails are affected
- Nails are painful or infected
- Over the counter treatments are not helping
- You are unsure of the cause
Early review helps guide appropriate treatment.

Further Reading and Hub Links
Visit our Dermatology, Skin and Allergies Health hub or browse more health topics in the AccessGP Knowledge Base.
If you are concerned about nail changes or possible nail infection, our GPs can assess your symptoms and advise on appropriate next steps.
Last reviewed by Dr Zamiel Hussain, GMC registered GP
Updated: 19 December 2025
